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A New Pharmacokinetic Model Describing the Biodistribution of Intravenously and Intratumorally Administered Superparamagnetic Iron Oxide Nanoparticles (SPIONs) in a GL261 Xenograft Glioblastoma Model

BACKGROUND: Superparamagnetic iron oxide nanoparticles (SPIONs) have displayed multifunctional applications in cancer theranostics following systemic delivery. In an effort to increase the therapeutic potential of local therapies (including focal hyperthermia), nanoparticles can also be administered...

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Publicat a:Int J Nanomedicine
Autors principals: Klapproth, Alexander P, Shevtsov, Maxim, Stangl, Stefan, Li, Wei Bo, Multhoff, Gabriele
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335747/
https://ncbi.nlm.nih.gov/pubmed/32669844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S254745
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