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BEON: A Functional Fluorescence Reporter for Quantification and Enrichment of Adenine Base-Editing Activity
Adenine base editor (ABE) is a new generation of genome-editing technology through fusion of Cas9 nickase with an evolved E. coli TadA (TadA∗) and holds great promise as novel genome-editing therapeutics for treating genetic disorders. ABEs can directly convert A-T to G-C in specific genomic DNA tar...
Uloženo v:
| Vydáno v: | Mol Ther |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Gene & Cell Therapy
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7335737/ https://ncbi.nlm.nih.gov/pubmed/32353322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.04.009 |
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