Exosomes From Induced Pluripotent Stem Cell–Derived Cardiomyocytes Promote Autophagy for Myocardial Repair

BACKGROUND: Induced pluripotent stem cells and their differentiated cardiomyocytes (iCMs) have tremendous potential as patient‐specific therapy for ischemic cardiomyopathy following myocardial infarctions, but difficulties in viable transplantation limit clinical translation. Exosomes secreted from...

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Pubblicato in:J Am Heart Assoc
Autori principali: Santoso, Michelle R., Ikeda, Gentaro, Tada, Yuko, Jung, Ji‐Hye, Vaskova, Evgeniya, Sierra, Raymond G., Gati, Cornelius, Goldstone, Andrew B., von Bornstaedt, Daniel, Shukla, Praveen, Wu, Joseph C., Wakatsuki, Soichi, Woo, Y. Joseph, Yang, Phillip C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335524/
https://ncbi.nlm.nih.gov/pubmed/32131688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.014345
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