Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons

Direct reprogramming of somatic cells has been demonstrated, however, it is unknown whether electrophysiologically-active somatic cells derived from separate germ layers can be interconverted. We demonstrate that partial direct reprogramming of mesoderm-derived cardiomyocytes into neurons is feasibl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chuang, Wenpo, Sharma, Arun, Shukla, Praveen, Li, Guang, Mall, Moritz, Rajarajan, Kuppusamy, Abilez, Oscar J., Hamaguchi, Ryoko, Wu, Joseph C., Wernig, Marius, Wu, Sean M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361100/
https://ncbi.nlm.nih.gov/pubmed/28327614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44840
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