Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as an In Vitro Model for Coxsackievirus B3-Induced Myocarditis and Antiviral Drug Screening Platform

RATIONAL: Viral myocarditis is a life-threatening illness that may lead to heart failure or cardiac arrhythmias. A major causative agent for viral myocarditis is the B3 strain of coxsackievirus, a positive-sense RNA enterovirus. However, human cardiac tissues are difficult to procure in sufficient e...

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Main Authors: Sharma, Arun, Marceau, Caleb, Hamaguchi, Ryoko, Burridge, Paul W., Rajarajan, Kuppusamy, Churko, Jared M., Wu, Haodi, Sallam, Karim I., Matsa, Elena, Sturzu, Anthony C., Che, Yonglu, Ebert, Antje, Diecke, Sebastian, Liang, Ping, Red-Horse, Kristy, Carette, Jan E., Wu, Sean M., Wu, Joseph C.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149868/
https://ncbi.nlm.nih.gov/pubmed/25015077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.303810
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