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Structure of avian influenza hemagglutinin in complex with a small molecule entry inhibitor
HA plays a critical role in influenza infection and, thus HA is a potential target for antivirals. Recently, our laboratories have described a novel fusion inhibitor, termed CBS1117, with EC(50) ∼3 μM against group 1 HA. In this work, we characterize the binding properties of CBS1117 to avian H5 HA...
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| Publicado en: | Life Sci Alliance |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Life Science Alliance LLC
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7335401/ https://ncbi.nlm.nih.gov/pubmed/32611549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000724 |
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