immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking

SUMMARY: B- and T-cell receptor repertoires of the adaptive immune system have become a key target for diagnostics and therapeutics research. Consequently, there is a rapidly growing number of bioinformatics tools for immune repertoire analysis. Benchmarking of such tools is crucial for ensuring rep...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioinformatics
Prif Awduron: Weber, Cédric R, Akbar, Rahmad, Yermanos, Alexander, Pavlović, Milena, Snapkov, Igor, Sandve, Geir K, Reddy, Sai T, Greiff, Victor
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Applications Notes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334888/
https://ncbi.nlm.nih.gov/pubmed/32154832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa158
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