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Brain Hepcidin Suppresses Major Pathologies in Experimental Parkinsonism

Despite intensive research on Parkinson disease (PD) for decades, this common neurodegenerative disease remains incurable. We hypothesize that abnormal iron accumulation is a common thread underlying the emergence of the hallmarks of PD, namely mitochondrial dysfunction and α-synuclein accumulation....

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Liang, Tuo, Qian, Zhong-Ming, Mu, Ming-Dao, Yung, Wing-Ho, Ke, Ya
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334576/
https://ncbi.nlm.nih.gov/pubmed/32623334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101284
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