Impairment of Hepcidin Upregulation by Lipopolysaccharide in the Interleukin-6 Knockout Mouse Brain

To find out whether the Interleukin-6 (IL-6)/signal transducer and activator of transcription 3 (STAT3) signaling pathway is involved in the expression of hepcidin in the mouse brain in vivo, we investigated the phosphorylation of STAT3, as well as the expression of hepcidin mRNA, ferroportin 1 (Fpn...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Zhang, Fa-Li, Hou, Hui-Min, Yin, Zhi-Nan, Chang, Lan, Li, Fe-Mi, Chen, Y.-J., Ke, Ya, Qian, Zhong-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681933/
https://ncbi.nlm.nih.gov/pubmed/29163042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00367
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