Uncoupling DNA damage from chromatin damage to detoxify doxorubicin

The anthracycline doxorubicin (Doxo) and its analogs daunorubicin (Daun), epirubicin (Epi), and idarubicin (Ida) have been cornerstones of anticancer therapy for nearly five decades. However, their clinical application is limited by severe side effects, especially dose-dependent irreversible cardiot...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Qiao, Xiaohang, van der Zanden, Sabina Y., Wander, Dennis P. A., Borràs, Daniel M., Song, Ji-Ying, Li, Xiaoyang, van Duikeren, Suzanne, van Gils, Noortje, Rutten, Arjo, van Herwaarden, Tessa, van Tellingen, Olaf, Giacomelli, Elisa, Bellin, Milena, Orlova, Valeria, Tertoolen, Leon G. J., Gerhardt, Sophie, Akkermans, Jimmy J., Bakker, Jeroen M., Zuur, Charlotte L., Pang, Baoxu, Smits, Anke M., Mummery, Christine L., Smit, Linda, Arens, Ramon, Li, Junmin, Overkleeft, Hermen S., Neefjes, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334570/
https://ncbi.nlm.nih.gov/pubmed/32554494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1922072117
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados