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Magnetically Directed Enzyme/Prodrug Prostate Cancer Therapy Based on β-Glucosidase/Amygdalin

BACKGROUND: β-Glucosidase (β-Glu) can activate amygdalin to kill prostate cancer cells, but the poor specificity of this killing effect may cause severe general toxicity in vivo, limiting the practical clinical application of this approach. MATERIALS AND METHODS: In this study, starch-coated magneti...

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Publicado en:Int J Nanomedicine
Main Authors: Zhou, Jie, Hou, Jing, Rao, Jun, Zhou, Conghui, Liu, Yunlong, Gao, Wenxi
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334483/
https://ncbi.nlm.nih.gov/pubmed/32636623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S242359
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