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Regulation of spatiotemporal limits of developmental gene expression via enhancer grammar
The regulatory specificity of a gene is determined by the structure of its enhancers, which contain multiple transcription factor binding sites. A unique combination of transcription factor binding sites in an enhancer determines the boundary of target gene expression, and their disruption often lea...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7334449/ https://ncbi.nlm.nih.gov/pubmed/32541043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917040117 |
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