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Spatiotemporal regulation of PEDF signaling by type I collagen remodeling

Dynamic remodeling of the extracellular matrix affects many cellular processes, either directly or indirectly, through the regulation of soluble ligands; however, the mechanistic details of this process remain largely unknown. Here we propose that type I collagen remodeling regulates the receptor-bi...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Kawahara, Kazuki, Yoshida, Takuya, Maruno, Takahiro, Oki, Hiroya, Ohkubo, Tadayasu, Koide, Takaki, Kobayashi, Yuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260941/
https://ncbi.nlm.nih.gov/pubmed/32385162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004034117
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