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Galectin-8 Enhances T cell Response by Promotion of Antigen Internalization and Processing

Galectin-8 (Gal-8) is a mammalian lectin endowed with immunostimulatory ability. In the present work, we demonstrate that Gal-8-glycan interactions on the surface of antigen-presenting cells (APCs) promote antigen binding and internalization, independently from antigen nature. Both Gal-8 and antigen...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Prato, Cecilia Arahí, Carabelli, Julieta, Campetella, Oscar, Tribulatti, María Virginia
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334376/
https://ncbi.nlm.nih.gov/pubmed/32619699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101278
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