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ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction

RATIONALE: Zona occludens 1 (ZO-1), encoded by the Tight Junction Protein 1 (TJP1) gene, is a regulator of paracellular permeability in epithelia and endothelia. ZO-1 interacts with the actin cytoskeleton, gap and adherens junction proteins, and localizes to intercalated discs in cardiomyocytes. How...

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Détails bibliographiques
Publié dans:Circ Res
Auteurs principaux: Dai, Wenli, Nadadur, Rangarajan D., Brennan, Jaclyn A., Smith, Heather L., Shen, Kaitlyn M., Gadek, Margaret, Laforest, Brigitte, Wang, Mingyi, Gemel, Joanna, Li, Ye, Zhang, Jing, Ziman, Bruce D., Yan, Jiajie, Ai, Xun, Beyer, Eric C., Lakata, Edward G., Kasthuri, Narayanan, Efimov, Igor R., Broman, Michael T., Moskowitz, Ivan P., Shen, Le, Weber, Christopher R.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334106/
https://ncbi.nlm.nih.gov/pubmed/32347164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.119.316415
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