B-cells improve overall survival in HPV-associated squamous cell carcinomas and are activated by radiation and PD-1 blockade.

PURPOSE: Characterize the role of B-cells on HPV-associated cancer patient outcomes and determine the effects of radiation and PD-1 blockade on B-cell populations. EXPERIMENTAL DESIGN: Tumor RNA sequencing data from over 800 HNSCC and cervical cancer patients, including a prospective validation coho...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Kim, Sangwoo Shawn, Shen, Sarek, Miyauchi, Sayuri, Sanders, Philip Dominick, Franiak-Pietryga, Ida, Mell, Loren K., Gutkind, J. Silvio, Cohen, Ezra E.W., Califano, Joseph, Sharabi, Andrew B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334097/
https://ncbi.nlm.nih.gov/pubmed/32193227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-3211
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