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Targeting the Complement Alternative Pathway Permits Graft Versus Leukemia Activity while Preventing Graft Versus Host Disease

PURPOSE: Application of allogeneic hematopoietic cell transplantation (allo-HCT) for patients with hematological disorders is limited by the development of graft-versus-host-disease (GVHD). Separation of GVHD and graft-versus-leukemia (GVL) remains a great challenge in the field. We investigated the...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Nguyen, Hung D., Alawieh, Ali, Bastian, David, Kuril, Sandeepkumar, Dai, Min, Daenthanasanmak, Anusara, Zhang, Mengmeng, Iamsawat, Supinya, Schutt, Steven, Wu, Yongxia, Sleiman, Mahdi, Shetty, Akshay, Atkinson, Carl, Sun, Shaoli, Varela, Juan, Tomlinson, Stephen, Yu, Xue-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334060/
https://ncbi.nlm.nih.gov/pubmed/31919135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-1717
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