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NSD3S stabilizes MYC through hindering its interaction with FBXW7

The MYC transcription factor plays a key role in cell growth control. Enhanced MYC protein stability has been found to promote tumorigenesis. Thus, understanding how MYC stability is controlled may have significant implications for revealing MYC-driven growth regulatory mechanisms in physiological a...

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Detalhes bibliográficos
Publicado no:J Mol Cell Biol
Main Authors: Gonzalez-Pecchi, Valentina, Kwan, Albert K, Doyle, Sean, Ivanov, Andrey A, Du, Yuhong, Fu, Haian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333476/
https://ncbi.nlm.nih.gov/pubmed/31638140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz098
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