Transient Decrease of Circulating and Tissular Dendritic Cells in Patients With Mycobacterial Disease and With Partial Dominant IFNγR1 Deficiency

Interferon-γ receptor 1 (IFNγR1) deficiency is one of the inborn errors of IFN-γ immunity underlying Mendelian Susceptibility to Mycobacterial Disease (MSMD). This molecular circuit plays a crucial role in regulating the interaction between dendritic cells (DCs) and T lymphocytes, thus affecting DCs...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Dotta, Laura, Vairo, Donatella, Giacomelli, Mauro, Moratto, Daniele, Tamassia, Nicola, Vermi, William, Lonardi, Silvia, Casanova, Jean-Laurent, Bustamante, Jacinta, Giliani, Silvia, Badolato, Raffaele
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333364/
https://ncbi.nlm.nih.gov/pubmed/32676075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01161
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