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BEM: Mining Coregulation Patterns in Transcriptomics via Boolean Matrix Factorization

MOTIVATION: The matrix factorization is an important way to analyze coregulation patterns in transcriptomic data, which can reveal the tumor signal perturbation status and subtype classification. However, current matrix factorization methods do not provide clear bicluster structure. Furthermore, the...

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Détails bibliographiques
Publié dans:Bioinformatics
Auteurs principaux: Liang, Lifan, Zhu, Kunju, Lu, Songjian
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332573/
https://ncbi.nlm.nih.gov/pubmed/31913438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz977
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