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Learning context-aware structural representations to predict antigen and antibody binding interfaces

MOTIVATION: Understanding how antibodies specifically interact with their antigens can enable better drug and vaccine design, as well as provide insights into natural immunity. Experimental structural characterization can detail the ‘ground truth’ of antibody–antigen interactions, but computational...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioinformatics
Hauptverfasser: Pittala, Srivamshi, Bailey-Kellogg, Chris
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332568/
https://ncbi.nlm.nih.gov/pubmed/32321157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa263
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