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Characterizing the actin-binding ability of Zasp52 and its contribution to myofibril assembly

In sarcomeres, α-actinin crosslinks thin filaments and anchors them at the Z-disc. Drosophila melanogaster Zasp52 also localizes at Z-discs and interacts with α-actinin via its extended PDZ domain, thereby contributing to myofibril assembly and maintenance, yet the detailed mechanism of Zasp52 funct...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liao, Kuo An, González-Morales, Nicanor, Schöck, Frieder
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332060/
https://ncbi.nlm.nih.gov/pubmed/32614896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232137
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