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Filamin actin-binding and titin-binding fulfill distinct functions in Z-disc cohesion
Many proteins contribute to the contractile properties of muscles, most notably myosin thick filaments, which are anchored at the M-line, and actin thin filaments, which are anchored at the Z-discs that border each sarcomere. In humans, mutations in the actin-binding protein Filamin-C result in myop...
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| Veröffentlicht in: | PLoS Genet |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5521747/ https://ncbi.nlm.nih.gov/pubmed/28732005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006880 |
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