Macrophages are the primary effector cells in IL-7-induced arthritis

Synovial macrophages are crucial in the development of joint inflammation and bone damage; however, the pathways that control macrophage remodeling in inflammatory M1 cells or bone-eroding osteoclasts are not fully understood. We determined that elevated IL-7R/CD127 expression is the hallmark of rhe...

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發表在:Cell Mol Immunol
Main Authors: Kim, Seung-jae, Chang, Huan J., Volin, Michael V., Umar, Sadiq, Van Raemdonck, Katrien, Chevalier, Aimee, Palasiewicz, Karol, Christman, John W., Volkov, Suncica, Arami, Shiva, Maz, Mehrdad, Mehta, Anjali, Zomorrodi, Ryan K., Fox, David A., Sweiss, Nadera, Shahrara, Shiva
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331600/
https://ncbi.nlm.nih.gov/pubmed/31197255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0235-z
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