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Amide Synthesis through the In Situ Generation of Chloro- and Imido-Phosphonium Salts

[Image: see text] We describe a methodology for the amidation of carboxylic acids by generating phosphonium salts in situ from N-chlorophthalimide and triphenylphosphine. Aliphatic, benzylic, and aromatic carboxylic acids can be transformed into their amide counter parts using primary and secondary...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Irving, Charles D., Floreancig, Jack T., Laulhé, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331200/
https://ncbi.nlm.nih.gov/pubmed/32637849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c02309
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