Proteus: An algorithm for proposing stabilizing mutation pairs based on interactions observed in known protein 3D structures

BACKGROUND: Protein engineering has many applications for industry, such as the development of new drugs, vaccines, treatment therapies, food, and biofuel production. A common way to engineer a protein is to perform mutations in functionally essential residues to optimize their function. However, th...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Barroso, José Renato M. S., Mariano, Diego, Dias, Sandro R., Rocha, Rafael E. O., Santos, Lucianna H., Nagem, Ronaldo A. P., de Melo-Minardi, Raquel C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330979/
https://ncbi.nlm.nih.gov/pubmed/32611389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03575-6
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