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A Computational Method to Propose Mutations in Enzymes Based on Structural Signature Variation (SSV)

With the use of genetic engineering, modified and sometimes more efficient enzymes can be created for different purposes, including industrial applications. However, building modified enzymes depends on several in vitro experiments, which may result in the process being expensive and time-consuming....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Mariano, Diego César Batista, Santos, Lucianna Helene, Machado, Karina dos Santos, Werhli, Adriano Velasque, de Lima, Leonardo Henrique França, de Melo-Minardi, Raquel Cardoso
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359350/
https://ncbi.nlm.nih.gov/pubmed/30650542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20020333
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