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Exploring the Post-Translational Enzymology of PaaA by mRNA Display
PaaA is a RiPP enzyme which catalyzes the transformation of two glutamic acid residues within a substrate peptide into the bicyclic core of Pantocin A. Here for the first time, we use mRNA display techniques to understand RiPP enzyme-substrate interactions to illuminate PaaA substrate recognition. A...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7330867/ https://ncbi.nlm.nih.gov/pubmed/32109054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c01576 |
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