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Initiating translation with D-amino acids
Here we report experimental evidence that the translation initiation apparatus accepts D-amino acids ((D)aa), as opposed to only L-methionine, as initiators. Nineteen (D)aa, as the stereoisomers to their natural L-amino acids, were charged onto initiator tRNA(fMet) (CAU) using flexizyme technology a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2441986/ https://ncbi.nlm.nih.gov/pubmed/18515548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1020708 |
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