Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis

Intrarenal calcium oxalate (CaOx) crystals induce renal tubular epithelial cells (TECs) injury and inflammation, which involve Toll-like receptor 4 (TLR4)/interferon regulatory factor 1 (IRF1) signaling. Additionally, infiltrating macrophages (Mϕs) might influence intrarenal CaOx crystals and CaOx-i...

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Veröffentlicht in:Theranostics
Hauptverfasser: Liu, Haoran, Yang, Xiaoqi, Tang, Kun, Ye, Tao, Duan, Chen, Lv, Peng, Yan, Libin, Wu, Xiaoliang, Chen, Zhiqiang, Liu, Jianhe, Deng, Yaoliang, Zeng, Guohua, Xing, Jinchun, Ye, Zhangqun, Xu, Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330860/
https://ncbi.nlm.nih.gov/pubmed/32641994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.44054
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