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Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis

Intrarenal calcium oxalate (CaOx) crystals induce renal tubular epithelial cells (TECs) injury and inflammation, which involve Toll-like receptor 4 (TLR4)/interferon regulatory factor 1 (IRF1) signaling. Additionally, infiltrating macrophages (Mϕs) might influence intrarenal CaOx crystals and CaOx-i...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Liu, Haoran, Yang, Xiaoqi, Tang, Kun, Ye, Tao, Duan, Chen, Lv, Peng, Yan, Libin, Wu, Xiaoliang, Chen, Zhiqiang, Liu, Jianhe, Deng, Yaoliang, Zeng, Guohua, Xing, Jinchun, Ye, Zhangqun, Xu, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330860/
https://ncbi.nlm.nih.gov/pubmed/32641994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.44054
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