Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes

Disturbed renal lipid metabolism, especially cholesterol dysregulation plays a crucial role in the pathogenesis of chronic kidney disease (CKD). We recently reported that angiotensin (Ang) II could induce cholesterol accumulation and injury in podocytes. However, the underlying mechanisms for these...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Yang, Qian, Hu, Jijia, Yang, Yingjie, Chen, Zhaowei, Feng, Jun, Zhu, Zijing, Wang, Huiming, Yang, Dingping, Liang, Wei, Ding, Guohua
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330847/
https://ncbi.nlm.nih.gov/pubmed/32642006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.45003
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