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Matrix Density Drives 3D Organotypic Lymphatic Vessel Activation in a Microfluidic Model of the Breast Tumor Microenvironment

Lymphatic vessels (LVs) have been suggested as a preferential conduit for metastatic progression in breast cancer, where a correlation between the occurrence of lymph node metastasis and an increased extracellular matrix (ECM) density has been reported. However, the effect of ECM density on LV funct...

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Foilsithe in:Lab Chip
Main Authors: Lugo-Cintrón, Karina M., Ayuso, José M., White, Bridget R., Harari, Paul M., Ponik, Suzanne, Beebe, David J., Gong, Max M., Virumbrales-Muñoz, María
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330815/
https://ncbi.nlm.nih.gov/pubmed/32297896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0lc00099j
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