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Breast Fibroblasts and ECM Components Modulate Breast Cancer Cell Migration through the Secretion of MMPs in a 3D Microfluidic Co-Culture Model

The extracellular matrix (ECM) composition greatly influences cancer progression, leading to differential invasion, migration, and metastatic potential. In breast cancer, ECM components, such as fibroblasts and ECM proteins, have the potential to alter cancer cell migration. However, the lack of in...

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Библиографические подробности
Опубликовано в: :Cancers (Basel)
Главные авторы: Lugo-Cintrón, Karina M., Gong, Max M., Ayuso, José M., Tomko, Lucas A., Beebe, David J., Virumbrales-Muñoz, María, Ponik, Suzanne M.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7281408/
https://ncbi.nlm.nih.gov/pubmed/32384738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12051173
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