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Handling multi-mapped reads in RNA-seq

Many eukaryotic genomes harbour large numbers of duplicated sequences, of diverse biotypes, resulting from several mechanisms including recombination, whole genome duplication and retro-transposition. Such repeated sequences complicate gene/transcript quantification during RNA-seq analysis due to re...

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Bibliografske podrobnosti
izdano v:Comput Struct Biotechnol J
Main Authors: Deschamps-Francoeur, Gabrielle, Simoneau, Joël, Scott, Michelle S.
Format: Artigo
Jezik:Inglês
Izdano: Research Network of Computational and Structural Biotechnology 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330433/
https://ncbi.nlm.nih.gov/pubmed/32637053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.06.014
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