Novel airway smooth muscle–mast cell interactions and a role for the TRPV4-ATP axis in non-atopic asthma

Mast cell–airway smooth muscle (ASM) interactions play a major role in the immunoglobulin (Ig)E- dependent bronchoconstriction seen in asthma but less is known about IgE-independent mechanisms of mast cell activation. Transient receptor potential cation channel, subfamily V, member 4 (TRPV4) activat...

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Publicat a:Eur Respir J
Autors principals: Bonvini, Sara J., Birrell, Mark A., Dubuis, Eric, Adcock, John J., Wortley, Michael A., Flajolet, Pauline, Bradding, Peter, Belvisi, Maria G.
Format: Artigo
Idioma:Inglês
Publicat: European Respiratory Society 2020
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330131/
https://ncbi.nlm.nih.gov/pubmed/32299856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.01458-2019
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