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Association study based on topological constraints of protein–protein interaction networks

The non-random interaction pattern of a protein–protein interaction network (PIN) is biologically informative, but its potentials have not been fully utilized in omics studies. Here, we propose a network-permutation-based association study (NetPAS) method that gauges the observed interactions betwee...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Guo, Hao-Bo, Qin, Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329836/
https://ncbi.nlm.nih.gov/pubmed/32612246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67875-w
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