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Gene essentiality and the topology of protein interaction networks

The mechanistic bases for gene essentiality and for cell mutational resistance have long been disputed. The recent availability of large protein interaction databases has fuelled the analysis of protein interaction networks and several authors have proposed that gene dispensability could be strongly...

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Detalhes bibliográficos
Main Authors: Coulomb, Stéphane, Bauer, Michel, Bernard, Denis, Marsolier-Kergoat, Marie-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559853/
https://ncbi.nlm.nih.gov/pubmed/16087428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2005.3128
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