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Gene essentiality and the topology of protein interaction networks

The mechanistic bases for gene essentiality and for cell mutational resistance have long been disputed. The recent availability of large protein interaction databases has fuelled the analysis of protein interaction networks and several authors have proposed that gene dispensability could be strongly...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Coulomb, Stéphane, Bauer, Michel, Bernard, Denis, Marsolier-Kergoat, Marie-Claude
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559853/
https://ncbi.nlm.nih.gov/pubmed/16087428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2005.3128
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