Identification by mass spectrometry and immunoblotting of xenogeneic antigens in the N- and O-glycomes of porcine, bovine and equine heart tissues

Animal bioprosthetic heart valves (BHV) are used to replace defective valves in patients with valvular heart disease. Especially young BHV recipients may experience a structural valve deterioration caused by an immune reaction in which α-Gal and Neu5Gc are potential target antigens. The expression o...

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Vydáno v:Glycoconj J
Hlavní autoři: Jin, Chunsheng, Cherian, Reeja Maria, Liu, Jining, Playà-Albinyana, Heribert, Galli, Cesare, Karlsson, Niclas G., Breimer, Michael E., Holgersson, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329767/
https://ncbi.nlm.nih.gov/pubmed/32542517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-020-09931-1
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