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Systems approach to rational combination therapy: PARP inhibitors
Poly (ADP-ribose) polymerase inhibitors (PARPi) have demonstrated activity across a broad spectrum of molecular backgrounds and tumor types, with the greatest activity observed in patients with aberrations in the homologous recombination DNA damage repair pathway. Despite remarkable responses in a s...
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| Published in: | Biochem Soc Trans |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7329579/ https://ncbi.nlm.nih.gov/pubmed/32379297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20191092 |
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