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A systematic review of the role of eculizumab in systemic lupus erythematosus-associated thrombotic microangiopathy

BACKGROUND: Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are characteristic of LN deposit in the kidney and activate immune mediated pathways including the complement system. Complete r...

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Bibliografski detalji
Izdano u:BMC Nephrol
Glavni autori: Wright, Rachael D., Bannerman, Fariba, Beresford, Michael W., Oni, Louise
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329551/
https://ncbi.nlm.nih.gov/pubmed/32605540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-020-01888-5
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