Eculizumab in gemcitabine-induced thrombotic microangiopathy: experience of the French thrombotic microangiopathies reference centre

BACKGROUND: Gemcitabine is a broadly prescribed chemotherapy, the use of which can be limited by renal adverse events, including thrombotic microangiopathy (TMA). METHODS: This study evaluated the efficacy of eculizumab, a monoclonal antibody targeting the terminal complement pathway, in patients wi...

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Veröffentlicht in:BMC Nephrol
Hauptverfasser: Grall, Maximilien, Daviet, Florence, Chiche, Noémie Jourde, Provot, François, Presne, Claire, Coindre, Jean-Philippe, Pouteil-Noble, Claire, Karras, Alexandre, Guerrot, Dominique, François, Arnaud, Benhamou, Ygal, Veyradier, Agnès, Frémeaux-Bacchi, Véronique, Coppo, Paul, Grangé, Steven
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8293501/
https://ncbi.nlm.nih.gov/pubmed/34284729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-021-02470-3
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