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Caught in the act: structural dynamics of replication origin activation and fork progression

This review discusses recent advances in single-particle cryo-EM and single-molecule approaches used to visualise eukaryotic DNA replication reactions reconstituted in vitro. We comment on the new challenges facing structural biologists, as they turn to describing the dynamic cascade of events that...

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Bibliografische gegevens
Gepubliceerd in:Biochem Soc Trans
Hoofdauteurs: Lewis, Jacob S., Costa, Alessandro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Portland Press Ltd. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329347/
https://ncbi.nlm.nih.gov/pubmed/32369549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20190998
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