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Caught in the act: structural dynamics of replication origin activation and fork progression

This review discusses recent advances in single-particle cryo-EM and single-molecule approaches used to visualise eukaryotic DNA replication reactions reconstituted in vitro. We comment on the new challenges facing structural biologists, as they turn to describing the dynamic cascade of events that...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Lewis, Jacob S., Costa, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329347/
https://ncbi.nlm.nih.gov/pubmed/32369549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20190998
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