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Early T cell Activation Metrics Predict GVHD In A Humanized Mouse Model of Hematopoietic Stem Cell Transplantation

Acute graft-vs-host disease (GVHD) is a frequent complication of hematopoietic transplantation, yet patient risk stratification remains difficult and prognostic biomarkers to guide early clinical interventions are lacking. We developed an approach to evaluate the potential of human T cells from hema...

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Pubblicato in:J Immunol
Autori principali: Hess, Nicholas J., Hudson, Amy W., Hematti, Peiman, Gumperz, Jenny E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329317/
https://ncbi.nlm.nih.gov/pubmed/32444392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000054
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