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Mice Engrafted With Human Fetal Thymic Tissue And Hematopoietic Stem Cells Develop Pathology Resembling Chronic GVHD

Chronic Graft versus Host Disease (cGVHD) is a significant roadblock to long-term hematopoeitic stem cell (HSC) transplantation success. Effective treatments for cGVHD have been difficult to develop, in part because of a paucity of animal models that recapitulate the multi-organ pathologies observed...

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Hlavní autoři: Lockridge, Jennifer L., Zhou, Ying, Becker, Yusof A., Ma, Shidong, Kenney, Shannon C., Hematti, Peiman, Capitini, Christian M., Burlingham, William J., Gendron-Fitzpatrick, Annette, Gumperz, Jenny E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755109/
https://ncbi.nlm.nih.gov/pubmed/23806772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2013.06.007
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