Cost-effectiveness analysis of genetic diagnostic strategies for Lynch syndrome in Italy

Lynch syndrome (LS) is an autosomal dominant condition caused by pathogenic variants in mismatch repair (MMR) genes that predispose individuals to different malignancies, such as colorectal cancer (CRC) and endometrial cancer. Current guidelines recommended testing for LS in individuals with newly d...

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Опубликовано в: :PLoS One
Главные авторы: Pastorino, Roberta, Basile, Michele, Tognetto, Alessia, Di Marco, Marco, Grossi, Adriano, Lucci-Cordisco, Emanuela, Scaldaferri, Franco, De Censi, Andrea, Federici, Antonio, Villari, Paolo, Genuardi, Maurizio, Ricciardi, Walter, Boccia, Stefania
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329085/
https://ncbi.nlm.nih.gov/pubmed/32609729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235038
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