Cost-effectiveness analysis of genetic diagnostic strategies for Lynch syndrome in Italy

Lynch syndrome (LS) is an autosomal dominant condition caused by pathogenic variants in mismatch repair (MMR) genes that predispose individuals to different malignancies, such as colorectal cancer (CRC) and endometrial cancer. Current guidelines recommended testing for LS in individuals with newly d...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pastorino, Roberta, Basile, Michele, Tognetto, Alessia, Di Marco, Marco, Grossi, Adriano, Lucci-Cordisco, Emanuela, Scaldaferri, Franco, De Censi, Andrea, Federici, Antonio, Villari, Paolo, Genuardi, Maurizio, Ricciardi, Walter, Boccia, Stefania
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329085/
https://ncbi.nlm.nih.gov/pubmed/32609729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235038
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