Pituitary dysfunction induced by immune checkpoint inhibitors is associated with better overall survival in both malignant melanoma and non-small cell lung carcinoma: a prospective study

BACKGROUND: Several immune-related adverse events (irAEs) are reported to be associated with therapeutic efficacy of immune checkpoint inhibitors, yet whether pituitary dysfunction, a life-threatening irAE, affects overall survival (OS) in patients with malignancies is unclear. This prospective stud...

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Publicado en:J Immunother Cancer
Main Authors: Kobayashi, Tomoko, Iwama, Shintaro, Yasuda, Yoshinori, Okada, Norio, Okuji, Takayuki, Ito, Masaaki, Onoue, Takeshi, Goto, Motomitsu, Sugiyama, Mariko, Tsunekawa, Taku, Takagi, Hiroshi, Hagiwara, Daisuke, Ito, Yoshihiro, Suga, Hidetaka, Banno, Ryoichi, Yokota, Kenji, Hase, Tetsunari, Morise, Masahiro, Hashimoto, Naozumi, Ando, Masahiko, Fujimoto, Yasushi, Hibi, Hideharu, Sone, Michihiko, Ando, Yuichi, Akiyama, Masashi, Hasegawa, Yoshinori, Arima, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2020
Assuntos:
Clinical/Translational Cancer Immunotherapy
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328763/
https://ncbi.nlm.nih.gov/pubmed/32606047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000779
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