Anti-thyroid antibodies and thyroid echo pattern at baseline as risk factors for thyroid dysfunction induced by anti-programmed cell death-1 antibodies: a prospective study

BACKGROUND: Anti-programmed cell death-1 (PD-1) antibodies can cause thyroid dysfunction. However, no predictive biomarkers enabling stratification of thyroid dysfunction risk have been identified. METHODS: A total of 209 patients treated with an anti-PD-1 antibody were evaluated for anti-thyroid an...

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Publicado no:Br J Cancer
Main Authors: Okada, Norio, Iwama, Shintaro, Okuji, Takayuki, Kobayashi, Tomoko, Yasuda, Yoshinori, Wada, Eri, Onoue, Takeshi, Goto, Motomitsu, Sugiyama, Mariko, Tsunekawa, Taku, Takagi, Hiroshi, Hagiwara, Daisuke, Ito, Yoshihiro, Suga, Hidetaka, Banno, Ryoichi, Hase, Tetsunari, Morise, Masahiro, Kanda, Mitsuro, Yokota, Kenji, Hashimoto, Naozumi, Ando, Masahiko, Fujimoto, Yasushi, Nagino, Masato, Kodera, Yasuhiro, Fujishiro, Mitsuhiro, Hibi, Hideharu, Sone, Michihiko, Kiyoi, Hitoshi, Gotoh, Momokazu, Ando, Yuichi, Akiyama, Masashi, Hasegawa, Yoshinori, Arima, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078193/
https://ncbi.nlm.nih.gov/pubmed/32009131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0736-7
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